rapamycin (Selleck Chemicals)
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rapamycin
Rapamycin, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1624 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rapamycin/Rapamycin/pmc13678578-1002-0-2
Average 96 stars, based on 1624 article reviews
Rapamycin, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1624 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rapamycin/Rapamycin/pmc13678578-1002-0-2
Average 96 stars, based on 1624 article reviews
rapamycin - by Bioz Stars,
2026-11
96/100 stars
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Cell-Signaling:Article Title: Blockade of radio-adaptive EZH2-mTOR signaling restores glioblastoma radiosensitivity Article Snippet: The antibodies used in this study included: anti-EZH2 (Cell Signaling Technology, 5246); anti-H3K27me3 (Cell Signaling Technology, 6944); anti-USP1 (Cell Signaling Technology, 8033); anti-p70S6K pT389 (Cell Signaling Technology, 9234); anti-p70S6K pS371 (Cell Signaling Technology, 9208); anti-p70S6K (Servicebio, GB111181); anti-p4EBP1 (Cell Signaling Technology, 2855); anti-4EBP1 (Immunoway, YT0022); and anti-β-Actin (Sigma, A1978). .. The reagents included GSK343 (Selleck, S7164); EPZ-6438 (APExBIO, A8221); Staining:Article Title: Serine synergizes with lipopolysaccharide to induce macrophage pyroptosis through extracellular Hsp90α and early skin immune microenvironment disruption in diabetic foot. Article Snippet: Background: The pathogenesis of early-stage skin lesions in diabetic foot (DF) remains poorly understood, and cannot be fully explained by conventional theories.. Skin microbiota dysbiosis has recently emerged as a critical factor, but the underlying mechanisms remain unclear.. Methods: In this study, we integrated metabolomics and metagenomics analyses of skin samples to investigate metabolic dysregulation driven by microbial dysbiosis. Activity Assay:Article Title: Serine synergizes with lipopolysaccharide to induce macrophage pyroptosis through extracellular Hsp90α and early skin immune microenvironment disruption in diabetic foot. Article Snippet: Background: The pathogenesis of early-stage skin lesions in diabetic foot (DF) remains poorly understood, and cannot be fully explained by conventional theories.. Skin microbiota dysbiosis has recently emerged as a critical factor, but the underlying mechanisms remain unclear.. Methods: In this study, we integrated metabolomics and metagenomics analyses of skin samples to investigate metabolic dysregulation driven by microbial dysbiosis. Lactate Dehydrogenase Assay:Article Title: Serine synergizes with lipopolysaccharide to induce macrophage pyroptosis through extracellular Hsp90α and early skin immune microenvironment disruption in diabetic foot. Article Snippet: Background: The pathogenesis of early-stage skin lesions in diabetic foot (DF) remains poorly understood, and cannot be fully explained by conventional theories.. Skin microbiota dysbiosis has recently emerged as a critical factor, but the underlying mechanisms remain unclear.. Methods: In this study, we integrated metabolomics and metagenomics analyses of skin samples to investigate metabolic dysregulation driven by microbial dysbiosis. Enzyme-linked Immunosorbent Assay:Article Title: Serine synergizes with lipopolysaccharide to induce macrophage pyroptosis through extracellular Hsp90α and early skin immune microenvironment disruption in diabetic foot. Article Snippet: Background: The pathogenesis of early-stage skin lesions in diabetic foot (DF) remains poorly understood, and cannot be fully explained by conventional theories.. Skin microbiota dysbiosis has recently emerged as a critical factor, but the underlying mechanisms remain unclear.. Methods: In this study, we integrated metabolomics and metagenomics analyses of skin samples to investigate metabolic dysregulation driven by microbial dysbiosis. other:Article Title: Mitotic assembly of respiratory supercomplexes ensures accurate cell division and fuels tumor growth Article Snippet: Control:Article Title: The role of rapamycin in neural tube defects: insights from bioinformatics analysis and experimental validation. Article Snippet: Neural tube defects (NTDs) are the most severe congenital malformations of the central nervous system.. Fetal developmental homeostasis disruptions heighten NTDs risk through aberrant maternal-fetal signaling and periconceptional medication exposure.. Rapamycin, an inhibitor of the mTOR signaling pathway, is a widely used clinical drug whose effects on embryonic neural development remain unclear. shRNA:Article Title: ACTB promotes ESCC progression by regulating the AKT-mTOR signaling pathway through an m 6 A-dependent mechanism. Article Snippet: .. The following validated shRNA sequences were used: shACTB-1: 5′-GGCTTTCGTGTAAATTATA-3′ shACTB-2: 5′-GTAATCTTCGCCTTAATAA-3′ shYTHDC2-1: 5′-GCATATATGGTTTAATAAA-3′ shYTHDC2-2: 5′-GGCATATATGGTTTAATAA-3′ Ivermectin (MCE, Cat#HY-15310), Concentration Assay:Article Title: ACTB promotes ESCC progression by regulating the AKT-mTOR signaling pathway through an m 6 A-dependent mechanism. Article Snippet: .. The following validated shRNA sequences were used: shACTB-1: 5′-GGCTTTCGTGTAAATTATA-3′ shACTB-2: 5′-GTAATCTTCGCCTTAATAA-3′ shYTHDC2-1: 5′-GCATATATGGTTTAATAAA-3′ shYTHDC2-2: 5′-GGCATATATGGTTTAATAA-3′ Ivermectin (MCE, Cat#HY-15310), In Vitro:Article Title: ACTB promotes ESCC progression by regulating the AKT-mTOR signaling pathway through an m 6 A-dependent mechanism. Article Snippet: .. The following validated shRNA sequences were used: shACTB-1: 5′-GGCTTTCGTGTAAATTATA-3′ shACTB-2: 5′-GTAATCTTCGCCTTAATAA-3′ shYTHDC2-1: 5′-GCATATATGGTTTAATAAA-3′ shYTHDC2-2: 5′-GGCATATATGGTTTAATAA-3′ Ivermectin (MCE, Cat#HY-15310), In Vivo:Article Title: ACTB promotes ESCC progression by regulating the AKT-mTOR signaling pathway through an m 6 A-dependent mechanism. Article Snippet: .. The following validated shRNA sequences were used: shACTB-1: 5′-GGCTTTCGTGTAAATTATA-3′ shACTB-2: 5′-GTAATCTTCGCCTTAATAA-3′ shYTHDC2-1: 5′-GCATATATGGTTTAATAAA-3′ shYTHDC2-2: 5′-GGCATATATGGTTTAATAA-3′ Ivermectin (MCE, Cat#HY-15310), Drug discovery:Article Title: Senotherapeutic potential against xeroderma pigmentosum. Article Snippet: Senotherapeutic drug screening agents The following agents were applied for senolytic drug screening: ABT-263 (Selleck, S1001), A-1331852 (Selleck, S7801), A-1155463 (Selleck, S7800), S63845 (MedchemExpress, HY-100741), BPTES (Selleck, S7753), RSL3 (Selleck, S8155), digoxin (Sigma, D6003), ouabain (Sigma, O3125), 17-DMAG (Selleck, S1142), ganetespib (Selleck, S1159), panobinostat (Selleck, S1030), and romidepsin (MedchemExpress, HY-15149). .. In addition, the following agents were applied for senomorphic drug screening: A485 (Selleck, S8740), acetylcysteine (Selleck, S1623), curcumin (Selleck, S1848), EF24 (MedchemExpress, HY-119272), metformin (Selleck, S5958), apremilast (Selleck, S8034), difamilast (MedchemExpress, HY-109085), abrocitinib (Selleck, S8765), baricitinib (Selleck, S2851), upadacitinib (Selleck, S8162), IFN alpha-IFNAR-IN-1 (Selleck, E2982), VBIT-4 (Selleck, S3544), |
